Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
نویسندگان
چکیده
While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin.
منابع مشابه
P 59: Non-Steroidal Anti-Inflammatory Drugs as a Prevention of Alzheimer Disease: Risks and Benefits
Alzheimer's disease (AD) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. The exact cause of Alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. This brings in mind using non-steroidal anti-inflammatory drugs (NSAID) as treatment or prevention of the disease. ...
متن کاملIsobolographic antinociception of non-steroidal anti-inflammatory drugs in rodent formalin orofacial pain
Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) induce antinociception through inhibition of cyclooxygenases. In this study was evaluated the effect of NSAIDs to induce antinociception either alone or in combination in the formalin orofacial test of rodent. Male mice were injected intraperitoneally with dexibuprofen, dexktoprofen, diclofenac meloxicam, metamizol, and...
متن کاملInvestigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. In this study, seven of NSAIDs were tested against two species of skin pathogenic fungi (dermatophytes). Percentage inhibition was determined for effective agents. Diclofenac, Aspirin and Naproxen showed muc...
متن کاملPnm-24: Pharmacologic Effect of Non-Steroidal Anti-Inflammatory Drugs in Reproductive System-(An Experimental Design
Background: Some patients that used Non-steroidal anti-inflammatory drug for a long time, as an analgesic, antipyretic or anti-inflammatory agent may be seen unusual effect of this drug on spermatogenesis and the level of blood testosterone hormone. The aim of this research is assess the effect of this drug on male-reproductive system functions Materials and Methods: This experimental research ...
متن کاملInvestigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. In this study, seven of NSAIDs were tested against two species of skin pathogenic fungi (dermatophytes). Percentage inhibition was determined for effective agents. Diclofenac, Aspirin and Naproxen showed muc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2010